An Unusual Huge Distal Femoral Giant Cell tumour of Bone (GCTB) in an Adult Male Patient in a Low Resource Setting: A Case Report

Abstract

The Giant cell tumour of bone (GCTB) is a benign but locally aggressive bone lesion, it accounts for 4-10% of all primary bone tumours. We present the case of a giant cell tumour of a 35-year-old male with a 3-year history of progressive left knee joint swelling. The swelling was progressive and initially painless but later became painful with walking. The Plain Anterior-posterior and lateral radiographs of the left knee showed an expansile osteolytic lesion involving the distal third of the femur with some sclerosis of the distal femoral segment and thinning of the cortex. Aspiration biopsy of the mass showed large numbers of osteoclast giant cells with spindle-shaped stromal cells. On account of these, a diagnosis of GCT of the left knee was confirmed. The patient had a wide excision of the tumour mass. The tumour grossly consisted of brown cheesy material and involved all the soft tissue around it. The patient had total knee replacement and did very well on follow-up.